Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
Q9DA01
(Eppin) with a FATCAT P-Value: 9.59e-07 and RMSD of 1.68 angstrom. The sequence alignment identity is 43.2%.
Structural alignment shown in left. Query protein Q9BQY6 colored as red in alignment, homolog Q9DA01 colored as blue.
Query protein Q9BQY6 is also shown in right top, homolog Q9DA01 showed in right bottom. They are colored based on secondary structures.
Q9BQY6 MGLSGLLPILVPFILLGDIQEPGHAEGILGKP--CPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCL----D---FRKIYAVC---HRRLAPAWP 88 Q9DA01 MKLSGFVSILVLFGLLARVQGPSLAD-LL-FPRRCPRFREECEHQERDLCTRDRDCPKKEKCCVFNCGKKCLNPQQDICSLPKDSGYCMAYFRRW---W- 94 Q9BQY6 PYHTGGTIKKTKICSEFIYGGSQGNNNNFQTEAICLVTC-KKYH-- 131 Q9DA01 -FN-----KENSTCQVFIYGGCQGNNNNFQSQSICQNACEKKSSLT 134
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
| Source | GO | Description |
|---|---|---|
| 1. PB | GO:0005737 | cytoplasm |
| 1. PB | GO:0032731 | positive regulation of interleukin-1 beta production |
| 1. PB | GO:0008191 | metalloendopeptidase inhibitor activity |
| 1. PB | GO:0044465 | modulation of sensory perception of pain in another organism |
| 1. PB | GO:0032760 | positive regulation of tumor necrosis factor production |
| 1. PB | GO:0090729 | toxin activity |
| 1. PB | GO:0050729 | positive regulation of inflammatory response |
| 1. PB | GO:0061844 | antimicrobial humoral immune response mediated by antimicrobial peptide |
| 1. PB | GO:0042151 | nematocyst |
| 1. PB | GO:0010466 | negative regulation of peptidase activity |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
| Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
|---|---|---|---|---|---|
| 1. PB | P0DJ81 | Kunitz-type U15-theraphotoxin-Hs1e | 2.67e-02 | 5.77e-06 | 0.014 |
| 1. PB | P0DJ82 | Kunitz-type kappaPI-theraphotoxin-Hs1c | 4.16e-03 | 7.85e-11 | 0.044 |
| 1. PB | D2Y2Q8 | Kunitz-type U15-theraphotoxin-Hhn1q | 4.05e-03 | 7.69e-09 | 0.016 |
| 1. PB | Q6ITB6 | Kunitz-type serine protease inhibitor scutellin-2 | 3.17e-02 | 5.78e-10 | 0.018 |
| 1. PB | D2Y2Q1 | Kunitz-type U15-theraphotoxin-Hhn1l | 4.55e-03 | 1.68e-07 | 0.048 |
| 1. PB | P0DMJ5 | PI-stichotoxin-Hcr2e | 1.53e-02 | 3.54e-02 | 0.025 |
| 1. PB | E7FL13 | Kunitz serine protease inhibitor Pr-mulgin 3 | 3.37e-02 | 9.33e-08 | 0.009 |
| 1. PB | B4ESA2 | Kunitz-type serine protease inhibitor PILP-1 | 8.72e-02 | 1.04e-09 | 0.032 |
| 1. PB | B7S4N9 | Kunitz-type serine protease inhibitor taicotoxin | 1.96e-02 | 1.95e-03 | 0.048 |
| 1. PB | C1IC53 | Protease inhibitor 4 | 3.94e-02 | 9.70e-10 | 0.032 |